Why Does Zoloft Cause Weight Gain?

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Of these three medications, bupropion (Wellbutrin) is the most consistently associated with weight loss. Several studies, including a 2019 meta-analysis of 27 studies, found that bupropion (Wellbutrin) was the only commonly used antidepressant associated with weight loss.

Which antidepressants cause the most weight gain?

The antidepressants most likely to cause weight gain include amitriptyline (Brand name: Elavil), mirtazapine (Remeron), paroxetine (Paxil, Brisdelle, Pexeva), escitalopram (Lexapro), sertraline (Zoloft), duloxetine (Cymbalta), and citalopram (Celexa).

How much weight does Zoloft make you gain?

Experts say that for up to 25% of people, most antidepressant medications — including the popular SSRI (selective serotonin reuptake inhibitor) drugs like Lexapro, Paxil, Prozac, and Zoloft — can cause a weight gain of 10 pounds or more.

Does Zoloft make you happy?

23, 2019 (HealthDay News) — Many people who take the antidepressant Zoloft report feeling better. But new research suggests the drug may be treating their anxiety, rather than their depression, at least in the early weeks.

Is it better to take Zoloft in the morning or at night?

Administer once daily either morning or evening. If Zoloft makes you drowsy, take it at bedtime. May be taken with or without food; however, this needs to be consistent. Talk to your doctor if your mood worsens or you experience any suicidal thoughts particularly during the first few months of therapy.

Can I lose weight while on Zoloft?

Summary. Some patients taking Zoloft for the treatment of common mental health conditions like depressive symptoms and anxiety may experience short term weight loss as a result of the loss of appetite that sometimes occurs as a patient’s body adjusts to the medication.

Which SSRI does not cause weight gain?

Bupropion was associated with the least amount of weight gain, close to none. Two others that also appeared to have less weight gain were amitriptyline and nortriptyline. Amitriptyline and nortriptyline are older drugs. Because newer drugs tend to have fewer side effects, those two aren’t prescribed as frequently.

Which SSRI is best for not gaining weight?

Antidepressants that do not cause weight gain

According to current scientific research, antidepressants that are least likely to cause weight gain are: Effexor (venlafaxine) Wellbutrin (bupropion) Nefazodone (however, this is rarely used because it can cause severe liver problems)

Which anxiety medication causes weight loss?

bupropion (Aplenzin, Forfivo, Wellbutrin); this has the most studies connecting it to weight loss. fluoxetine (Prozac); results vary though some people experience weight loss. duloxetine (Cymbalta); while results are unclear, some people report weight loss.

How can I avoid gaining weight on antidepressants?

How to Avoid Antidepressant-Related Weight Gain

  1. Causes.
  2. Talk to Your Doctor.
  3. Ask About Switching Medications.
  4. Get a Medical Checkup.
  5. Add Diet and Exercise.

How fast do you lose weight on Wellbutrin?

A 2012 study found that obese adults who took bupropion SR (standard release) in 300mg or 400mg doses lost 7.2% and 10% of their body weight, respectively, over 24 weeks and maintained that weight loss at 48 weeks (Anderson, 2012).

What happens if you drink on Zoloft?

Mixing Zoloft with alcohol can exacerbate the symptoms of an upset stomach, possibly resulting in vomiting. Alcohol is a central nervous system depressant that by itself can cause depression. The consumption of alcohol can also worsen the symptoms of depression and make Zoloft less effective in treating these symptoms.

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Is 150 mg of Zoloft a lot?

Your doctor may adjust your dose as needed. However, the dose is usually not more than 150 mg per day throughout your menstrual cycle or 100 mg per day if you are only taking it during your premenstrual time. Children—Use and dose must be determined by your doctor.

What does Zoloft withdrawal feel like?

Sertraline withdrawal symptoms may persist for anywhere from a few days to a few weeks after your last dose. The most common symptoms include flu-like symptoms, dizziness, irritability, nausea, headache, insomnia and sensory disturbances.

Does Zoloft suppress appetite?

As with all medications, Zoloft may cause certain unwanted side effects. 1 The most commonly experienced in those taking Zoloft include: Decreased appetite.

Which causes more weight gain Prozac or Zoloft?

That being said, one study published in 2016 in the Journal of Clinical Medicine found that Zoloft can lead to an overall greater weight gain than Prozac when taken long-term. The study found that people taking Prozac for two years gained an average of 4.6 pounds.

Is 25 mg Zoloft enough for anxiety?

The right dosage of Zoloft for anxiety varies by the severity of anxiety and whether the patient has other medical conditions. In general, though, the initial therapeutic dosage of Zoloft for anxiety is 25 mg or 50 mg per day.

What is better Prozac or Zoloft?

In a double-blind, clinical trial, both Zoloft and Prozac improved depression based on different scores for depression and anxiety as well as sleep. While both SSRIs were found to be effective, Zoloft was found to have lower severity of side effects.

Does Zoloft give you energy?

When taken correctly, Zoloft can make people feel less anxious or fearful, and it can reduce the urge to perform repeated tasks. It can improve sleep quality, appetite, energy levels, restore interest in daily life, and reduce unwanted thoughts and panic attacks.

How does Zoloft make you feel at first?

Your doctor may start you on a low dose and gradually increase the dose over time. It’s common to experience headaches, nausea, and fatigue during your first week on Zoloft. These side effects often get better over the first week or two.

What can I take to help me sleep while on Zoloft?

But for some people, SSRIs can cause insomnia, so your doctor may have you take these in the morning, sometimes with an additional medicine for a short time to help people sleep at night.



Sedating antidepressants that can help you sleep include:

  1. Trazodone (Desyrel)
  2. Mirtazapine (Remeron)
  3. Doxepin (Silenor)

How long should I stay on sertraline?

Once you’re feeling better it’s likely that you’ll continue to take sertraline for several more months. Most doctors recommend that you take antidepressants for 6 months to a year after you no longer feel depressed.

Can you have a glass of wine on Zoloft?

Healthcare professionals advise that people avoid drinking alcohol when taking Zoloft. This is because both drugs can cause similar side effects. Taking both together may make the side effects worse. Alcohol can also worsen the symptoms of depression because it is a central nervous system depressant.

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