What Is Pulegone Used For?


Pulegone is a monoterpene found in many plants, such as peppermint and catnip, and it is the main constituent of pennyroyal and blue mint bush essential oils.

Where does pulegone come from?

Pulegone is derived from many different plant species, including the aforementioned pennyroyal, as well as many types of evergreen shrubs, corn mint, orange mint, peppermint, spearmint and blackcurrant, the palo santo tree, and the plant known as creeping Charlie, among others.

Is pulegone aromatic?

Isopulegone and pulegone derivatives have a minty, herbaceous aroma. With the exception of the acetate ester (No. 756), all the members of this group occur in peppermint oil, pennyroyal oil, and citrus peel oil.

Is pulegone toxic?


5.4-9 g pulegone, ca. 90-150 mg/kg bw for a 60 kg person; calculated with a relative density of 0.9 as for peppermint oil) resulted in moderate to severe toxicity and ingestion of greater than 15 ml (corresponding to ca. 8-13 g pulegone, ca. 130- 215 mg/kg bw for a 60 kg person) resulted in death.

Is pulegone a carcinogen?

Pulegone, a constituent of oil extracts prepared from mint plants, including peppermint, spearmint and pennyroyal, is a carcinogen that causes hepatic carcinomas, pulmonary metaplasia, and other neoplasms on oral administration in rodents.

Is Pulegone in peppermint oil?

Peppermint Oil is composed primarily of menthol and menthone. Other possible constituents include pulegone, menthofuran, and limone. Most of the safety test data concern Peppermint Oil.

How much does Pulegone cost?

No typical dose was found in the literature for pulegone. According to literature reports on levels of pulegone present in M. piperita oils, two capsules of 225 mg of oil taken twice per day could contain an amount of pulegone of between 4.5 and 41.4 mg (0.5–4.6%) (Smith & Levi, 1961).

What are the benefits of peppermint?

Possible health benefits. Peppermint is a popular traditional remedy for a number of conditions. It is believed to have calming effects. It is used to treat flatulence, menstrual pains, diarrhea, nausea, depression-related anxiety, muscle and nerve pain, the common cold, indigestion, and IBS.

Is smelling peppermint oil safe?

While some of the proposed benefits of peppermint oil come from anecdotal evidence, research suggests peppermint oil may be beneficial for IBS and other digestive conditions, as well as pain relief. Peppermint oil is generally safe, but it can be toxic when taken in very large doses.

Is peppermint extract good for skin?

Derived from the peppermint leaf, Peppermint Extract is a natural analgesic and antiseptic best known for its ability to help relieve skin irritations. … As redness and minor irritations are reduced, skin is left toned and refreshed.

Is menthol a carcinogen?

Purpose: Menthol smoking may lead to a greater increase in lung-cancer risk than smoking of nonmentholated cigarettes. Mentholation of cigarettes adds additional carcinogenic components to cigarette smoke and increases retention times for cigarette smoke in the lungs.

Why is menthol bad for you?

Serious effects include seizures, coma, and death. Menthol can cause eye and skin irritation. When used on the skin, menthol is typically diluted into a “carrier oil”, lotion, or other vehicle. If a high-percentage menthol product is applied to the skin, irritation and even chemical burns have been reported.

Does menthol hurt your lungs?

Menthol has a cooling and anesthetic (or pain killing) effect. … As a result, menthol smokers may inhale more deeply, hold the smoke in the lungs longer, and get more exposure to the dangerous chemicals in cigarette smoke.


What are the benefits of menthol?

Depending on the dose and form, menthol can be used to relieve coughs; help control plaque or kill bacteria that can contribute to the development of gingivitis; relieve oral discomfort associated with canker sores, injury of the mouth and gums, sore throat, fever blisters, or cold sores; relieve minor aches and pains …

What are the benefits of peppermint oil for skin?

“Peppermint oil naturally cleanses the skin and has antiseptic and antibacterial properties. It has a cooling effect which soothes irritation and inflammation due to acne,” said Dr. Debra Jaliman, a New York City-based dermatologist, assistant professor of dermatology at the Icahn School of Medicine.

Does peppermint oil have side effects?

Possible side effects of peppermint oil taken orally include heartburn, nausea, abdominal pain, and dry mouth. Rarely, peppermint oil can cause allergic reactions. Capsules containing peppermint oil are often enteric-coated to reduce the likelihood of heartburn.

Does peppermint oil really grow hair?

Peppermint oil can cause a cold, tingling feeling when it increases circulation to the area it’s applied to. This can help promote hair growth during the anagen (or growing) phase. One study found that peppermint oil, when used on mice, increased the number of follicles, follicle depth, and overall hair growth.

Are essential oils bad for lungs?

External use of an essential oil probably won’t put you at risk for anything, unless you happen to have allergies. So, if the scent of lavender wafting through the air helps you relax and unwind—and you don’t notice any other problems—it’s probably OK for your lungs to use essential oils, Dr. Buhr says.

What does it mean if an essential oil smells bad to you?

The oil smells bad. You don’t get the same effects from it as you used to – even if it still smells as wonderful as ever. It causes an adverse reaction that you’ve never experienced with this oil before. (This can also be a sign that you’ve become sensitized to an oil and therefore should avoid it forevermore.

Which essential oils are toxic to humans?

Highly toxic essential oils include camphor, clove, lavender, eucalyptus, thyme, tea tree, and wintergreen oils, the researchers noted. Many essential oils can cause symptoms such as agitation, hallucinations and seizures.

Is peppermint good for lungs?

The menthol in peppermint works as a decongestant, shrinking swollen membranes in the nose and making it easier to breathe, and also helps loosen mucus that has collected in the lungs. Peppermint may also help prevent a sickness from coming on in the first place.

How does peppermint affect the brain?

Peppermint in many forms such as tea, candy, and oil can be used to help improve mental awareness. The menthol “stimulates the Hippocampus area of the brain which controls mental clarity and memory. … use it increases the oxygen count in your blood, increasing the flow to your brain causing you to be more attentive.

Is peppermint good for the heart?

It seems that peppermint has a lowering effect on the heart rate and the systolic blood pressure. Yet in another study, peppermint aroma was administered by nose but no significant effect in both heart rate and blood pressure was observed.

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